PGD Overview

PGD is a method to determine whether there are any genetic anomalies on the embryos created via IVF treatment.

Normal IVF treatment is performed on the female wishing to do PGD. Eggs are collected and fertilized with sperm using microinjection (ICSI). After fertilization, genetic screening is performed on the embryos in order to only transfer the healthy embryos. This enables genetic testing of embryos and results in pregnancy without any genetic anomaly on the tested chromosomes.

Screening for several genetic disorders is performed before the transfer of healthy embryos to the female. Thanks to PGD (Preimplantation Genetic Diagnosis)  genetic disorders like Down’s syndrome, Monosomy and Trisomy can be screened. Chromosomes (13, 15, 16, 17, 18, 21, 22, X, Y) are checked in PGD-9 testing. Since gender chromosomes are also screened, gender selection can also be performed on cases where some genetic anomalies can pass via the gender chromosome.

    With PGD, it is also possible to detect numerical chromosome anomalies such as Monosomy or Trisomy (Down Syndrome, other Trisomies), single gene disorders (thalasemmia, cystic fibrosis, hemophilia A1 and B1, muscular dystrophia, sickle cell anemia, neurofibromatozis, fanconi anemia…) in advance. PGD can be applied to do gender selection when there are inherited diseases related to the X chromosome, and when medical gender determination needs to be done.


    Advantages of PGD in Cyprus

    • Choosing the healthy embryos of the elder females.
    • Increase in the implantation rate with the transfer of healthy embryos in cases with repetitive implantation failures.
    • Decrease in the multiple pregnancy.
    • Prevention of abortion due to transfer of healthy embryo before pregnancy occurs.
    • Increase in the clinical pregnancy rate.
    • Baby's sex determination before pregnancy due to medical reasons.
    • Ranked #7 IVF clinic in Europe (official GCR report)

    To whom and how is PGD (Preimplantation Genetic Diagnosis) performed?

    1. It is decided by our doctor and the genetic consultant whether it is required to apply PGD and this is agreed with the patient.
    2. The female is prepared for the IVF procedure.
    3. The doctor determines appropriate period for the collection of eggs.
    4. Sperm and egg are fertilized in the laboratory environment with a process called microinjection.
    5. Biopsy is carried out on the embryos that have appropriately developed in the laboratory environment.
    6. Genetic screening of the biopsy cell is performed.
    7. Embryo transfer is performed with the embryos whose genetic screenings were performed. Any excess embryos are frozen.




    Even though it is possible to only check the XY chromosomes for PGD/PGS patients, 9 and 24 chromosome checks are offered for patents in need of a more detailed genetic anomaly testing of their embryos.

    The PGD/PGS method accuracy is 99.9%.

    The success rate varies from couple to couple based on their fertility and age. The success rates are similar to a normal IVF treatment and can be as high as 60%.

    Let us make the dream come true

    Dunya IVF's team of experts will be happy to inform you regarding all fertility treatment options available, and recommend the optimal way forward for your specific circumstances. Contact us today and let us help you make the dream of parenthood a reality!

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